News

2013

-Structural basis for ion permeation in GLIC (EMBO J., Jan 2013) a pentameric bacterial ligand-gated ion channel
-Structural basis for alcohol potentiation in GLIC, Nature Communic., April 2013

2012

New structures on DNA polymerases
-DNA pol B from P. abyssi by J. Gouge et al. (JMB)
-Snapshots along the catalytic cycle of Tdt: Terminal deoxynucleotidyl transferase caught in action (J. Gouge et al., submitted to JMB)

New structures for ligand-gated ion channels
-A locally-closed form for GLIC here
-A review on cys-loop receptors here
-The paper on general anesthetics is here
-The structure of the open form is here

2011

AquaSAXS, a web-based software to calculate SAXS spectra from PDB coordinates, including the solvent density predicted by AquaSol, is now available on-line. See article.
The corresponding software Aquasol to calculate solvation maps is also on line (see article).

2010

A meeting in I. Pasteur of the France-Stanford Exchange Program (September)

2009

MinActionPath was updated (NewPath) to accept up to 10,000 atoms thanks to Patrice Koehl (UC Davis, USA).

2008

The dipolar solvent model was described in Biophysical Journal (coll. H. Orland).
The web server and new implementation due to P. Koehl (AquaSol) is here.

2007

MinActionPath web server: Generate the most probable trajectory between two known structural forms of the same macromolecule (Franklin et al., 2007).

2006

NOMAD-Ref web server Normal Mode Analysis, Deformation and Refinement	PDB_Hydro web server Mutation & Solvation: Dipolar Poisson-Boltzmannn

Introduction

Go to Main site for more details on the group activities.